FuncZyme Database

Curated enzyme activities, computational substrate predictions, and interactive prediction tools for plant enzyme families.

About the Curated Activities Dataset

FuncFetch is an automated workflow combining NCBI E-Utilities, OpenAI GPT-4, and Zotero to screen thousands of journal articles and extract experimentally validated enzyme activities. Extracted data passes through manual curation before publication.

  • Flagged Abstracts: PubMed-screened candidate papers (Step 2)
  • Minimally Curated Set: GPT-4-extracted activities, light curation (Step 5)
  • Verified Set: Fully manually verified entries (Step 6)

Funded by the NSF IOS-Plant Genome Research Program Award #2310395. See also: bioRxiv preprint.

Download Curated Activities

FamilyFlagged AbstractsMinimally CuratedVerified Set
(Di)oxygenaseDownloadDownload
AminotransferaseDownloadDownload
BAHD acyltransferaseDownloadDownloadDownload
Cytochrome P450DownloadDownload
GDSL lipase/esteraseDownloadDownload
MethyltransferaseDownloadDownload
PeroxidaseDownloadDownload
Polyketide synthaseDownloadDownload
UDP glycosyltransferaseDownloadDownload