FuncZyme Database
Curated enzyme activities, computational substrate predictions, and interactive prediction tools for plant enzyme families.
About the Curated Activities Dataset
FuncFetch is an automated workflow combining NCBI E-Utilities, OpenAI GPT-4, and Zotero to screen thousands of journal articles and extract experimentally validated enzyme activities. Extracted data passes through manual curation before publication.
- —Flagged Abstracts: PubMed-screened candidate papers (Step 2)
- —Minimally Curated Set: GPT-4-extracted activities, light curation (Step 5)
- —Verified Set: Fully manually verified entries (Step 6)
See the FuncFetch paper for more detail: 10.1093/bioinformatics/btae756.
Funded by the NSF IOS-Plant Genome Research Program Award #2310395.
Download Curated Activities
| Family | Flagged Abstracts | Minimally Curated | Verified Set |
|---|---|---|---|
| (Di)oxygenase | Download | Download | — |
| Aminotransferase | Download | Download | — |
| BAHD acyltransferase | Download | Download | Download |
| Cytochrome P450 | Download | Download | — |
| GDSL lipase/esterase | Download | Download | — |
| Methyltransferase | Download | Download | — |
| Peroxidase | Download | Download | — |
| Polyketide synthase | Download | Download | — |
| UDP glycosyltransferase | Download | Download | — |